Evaluating thin-cake pressure filtration using the BHS Autopress technology
Abstract: Thin-cake pressure filtration technology offers an alternative to agitated nutsche filters and centrifuges for solid-liquid separation, cake washing, and drying.
Solid-liquid separation and cake washing are integral steps in the production of bulk or final pharmaceutical products. Each step must be optimized, along with the downstream dryer.
Complicating this process is the number of competing technologies and options that can be employed to accomplish these steps. For example, most pharmaceutical processes will use either an agitated nutsche filter or a centrifuge for the separation and washing step.
This article discusses the use of the thin-cake Autopress pressure filter as an alternative to agitated nutsche filters and centrifuges. The results are applicable to specialty chemical and other applications with similar process crystals and requirements.
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